By Ellen M. Levee (auth.), Michael S. Goligorsky MD, PhD (eds.)
Today's investigator, crushed via the data avalanche, could locate it tricky to research rising advances in know-how. In Renal sickness: innovations and Protocols, prime specialists distill their adventure into undemanding equipment for learning fluid-electrolyte homeostasis and kidney functionality in health and wellbeing and sickness. defined in step by step element, the options circulate from the molecular point to the full organism, and from basic versions to integrative body structure. the following the researcher will locate proven ailment versions, equipment for optimizing renal illness examine, in addition to a lot assist in identifying imaging ideas for reports of the kidney's constitution and serve as in healthiness, sickness, and through embryonic improvement. matters lined contain molecular diagnostics, suggestions for learning the molecular mechanisms of kidney ailment, technical skill to evaluate the sensible correlates of affliction, and the making plans of scientific trials. as well as distinct directions, every one state-of-the-art procedure contains troubleshooting suggestion, lists of reagents, and pointers on fending off pitfalls.
state of the art and hugely sensible, Renal sickness: innovations and Protocols is not just a vade mecum for the various strategies hired to review the kidney in health and wellbeing and illness this present day, but in addition a effortless consultant for the uninitiated, and a considerate seek advice for the skilled researcher.
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In the following section, we summarize our experience with this model. 3. 1. Dyslipidemia An important feature of the metabolic syndrome and a cardinal phenotype of the male obese ZSF1 rat is abnormally high plasma levels of cholesterol and triglycerides. In this regard, male obese ZSF1 rats are similar to male obese SHHF/Mcc-facp rats, and both of these strains have much higher cholesterol and triglyceride levels compared with male SHR, WKY, lean SHHF/Mcc-facp or lean ZSF1 rats (20). Table 1 compares plasma lipid levels in male obese ZSF1 vs male lean ZSF1 at various ages.