By Donald J. Voet, Judith G. Voet
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The "Gold Standard" in Biochemistry textual content books, Biochemistry 4e, is a latest vintage that has been completely revised. Don and Judy Voet clarify biochemical innovations whereas providing a unified presentation of existence and its edition via evolution. accommodates either classical and present examine to demonstrate the historic resource of a lot of our biochemical knowledge.
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Extra info for Biochemistry (4th Edition)
C. Mitochondria Are the Site of Oxidative Metabolism Figure 1-7 Scanning electron micrograph of a fibroblast. ] cell specifies around 800 megabytes of information—about 200 times the information content of this text]. Within the nucleus, the genetic information encoded by the DNA is transcribed into molecules of RNA (Chapter 31), which, after extensive processing, are transported to the cytoplasm (in eukaroytes, the cell contents exclusive of the nucleus), where they direct the ribosomal synthesis of proteins (Chapter 32).
Moreover, one of the hallmarks of life is that the rates of its reactions are so tightly regulated that there is rarely an unsatisfied need for a reactant in a metabolic pathway or an unnecessary buildup of some product. Metabolism has been traditionally (although not necessarily logically) divided into two major categories: 1. Catabolism or degradation, in which nutrients and cell constituents are broken down so as to salvage their components and/or to generate energy. 2. Anabolism or biosynthesis, in which biomolecules are synthesized from simpler components.
A simpler classification scheme, which is based on cell wall properties, distinguishes three major types of prokaryotes: the mycoplasmas, the gram-positive bacteria, and the gram-negative bacteria. Mycoplasmas lack the rigid cell wall of other prokaryotes. 12 m in diameter, Fig. 1-1) and possess ϳ20% of the DNA of an E. coli. Presumably this quantity of genetic information approaches the minimum amount necessary to specify the essential metabolic machinery required for cellular life. Gram-positive and gram-negative bacteria are distinguished according to whether or not they take up gram stain (a procedure developed in 1884 by Christian Gram in which heat-fixed cells are successively treated with the dye crystal violet and iodine and then destained with either ethanol or acetone).