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By Suzanne De La Monte

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Stolk, H. F. van, H. A. Pols, A. Hofman, and M. M. Breteler, 1999, Diabetes mellitus and the risk of dementia: The Rotterdam Study: Neurology, v. 53, no. 9, p. 1937-1942. Pimplikar, S. , R. A. Nixon, N. K. Robakis, J. Shen, and L. H. , v. 30, no. 45, p. 14946-14954. Saykin, A. J. , v. 6, no. 3, p. 265-273. , and T. , v. 113, no. 11, p. 16251644. , Maslowski N. , 2009, Neural correlates of Alzheimer's disease and mild cognitive impairment: A systematic and quantitative meta-analysis involving 1351 patients.

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3. 1-3). Neurons, astroglia or microglia were identified by immunohistochemical staining using anti-NF, anti-MAP-2, and anti-GFAP or anti-CD11b, respectively. Double labeling immunohistochemistry with anti- 36 Alzheimer’s Disease Pathogenesis-Core Concepts, Shifting Paradigms and Therapeutic Targets NF (Fig. 1A) and anti-APP (Fig. 1B) antibodies clearly demonstrated the co-localization of NF and APP proteins in swollen and dystrophic nerve fibers at 1day after TBI (Fig. 1C). At 7 days after cortical traumatic injury, MAP-2-positive nerve cell cytoplasm (Fig.

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